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. 2020 Sep 12;25(18):4191. doi: 10.3390/molecules25184191

Scheme 3.

Scheme 3

Synthesis of title compounds with secondary amino groups. Reagents and conditions: (a) NaN3, dimethylformamide (DMF), 50–60 °C; (b) 1. triphenylphosphine, tetrahydrofuran; 2. HCl (H2O); (c) 1. CH3ONa, CH3OH, 2. 2-nitrilebenzaldehyde, CHCl3; (d) NaBH4, CH3OH.