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. Author manuscript; available in PMC: 2021 Feb 24.
Published in final edited form as: Nat Chem. 2020 Aug 24;12(10):952–961. doi: 10.1038/s41557-020-0514-4

Fig. 5 |. Proteomics analysis of HUVECs treated with TGP-377.

Fig. 5 |

a, Volcano plot showing the relative fold changes of >4,000 detected proteins. Data are reported as the mean of three biologically independent replicates (n= 3). The statistical significance was determined by a two-sided Student’s t-test and was not adjusted for multiple comparisons. b, STRING analysis of the 160 proteins affected by TGP-377. The analysis reported interaction scores of >0.9 (highest confidence) and is consistent with previous studies of VEGFA upregulation (Supplementary Table 7).