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. 2020 Oct 6;20(6):155. doi: 10.3892/etm.2020.9284

Figure 1.

Figure 1

Alterations in miRNA-29a, ZO-1, CLDN1 and the JC in the colon mucosa of patients with IBS-D. Relative expression of (A) miRNA-29a, (B) ZO-1 and CLDN1 was detected by reverse transcription-quantitative PCR. **P<0.01 vs. control. (C) Staining of the JC between colonic epithelium observed by transmission electron microscopy. n=3. Magnification, x20,000. IBS-D, diarrhea-predominant irritable bowel syndrome; miRNA, microRNA; ZO-1, tight junction protein ZO-1; CLDN1, claudin-1; JC, junctional complex.