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. 2020 Oct 7;20(6):159. doi: 10.3892/etm.2020.9288

Figure 4.

Figure 4

Pathological of rat brain tissue from different groups (n=5). (A) Representative hematoxylin and eosin staining images of rat brain tissues in each group. Brain tissues from the Normal group showed regular structures without obvious pathological damage, whereas the other groups demonstrated pathological damage of varying degrees, with pyknosis of nerve cells (indicated by arrows). Damage degree was less severe in Ad-miR-132 group and Ad-siMAPK1 group. Magnification, x200. Scale bar, 25 µm. (B) Quantitative results of pathological damages. *P<0.05 vs. Normal group; #P<0.05 vs. Model group; %P<0.05 vs. Ad-miR-132 NC group; &P<0.05 vs. Ad-miR-132 group; $P<0.05 vs. Ad-siMAPK1 NC group; @P<0.05 vs. Ad-siMAPK1 group. NC, negative control; miR, microRNA; si, small interfering.