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Magnetic resonance imaging signal characteristics and pathobiology of endplate modic degenerative marrow changes
| Modic classification | T1 signal characteristics | T2 signal characteristics | Gadolinium contrast enhancement | Pathobiology |
|---|---|---|---|---|
| Type I | Low | High | (+) Present | Marrow oedema (or inflammation) |
| Type II | High | High | (–) Absent | Fatty marrow conversion |
| Type III | Low | Low | (–) Absent | Subchondral bone sclerosis |
