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Mean performance (± SE) across time awake for PVT number of lapses (top) and LSNR (bottom) as a function of caffeine dose. Upward corresponds to greater impairment for lapses, while downward corresponds to greater impairment for the LSNR. Dashed vertical lines denote the times of gum administration. Triangles at the top of each panel indicate statistically significant differences by bout between 0 and 200 mg (dark gray), 0 and 300 mg (light gray), and 200 and 300 mg (open light gray)
