Table 2. Normalized protein expression (NPX) values.
Benign tumors vs. cancer, p < 0.05.
| Benign | Cancer | |||
|---|---|---|---|---|
| Protein | Mean (sd) | Mean (sd) | Adj. p-vala | Rank |
| WFDC2 | 7.37 (0.72) | 8.33 (0.64) | <0.001 | 1 |
| MUC-16 | 4.73 (1.93) | 6.55 (1.40) | <0.001 | 2 |
| MK | 7.15 (0.86) | 8.04 (0.84) | <0.001 | 3 |
| FR-alpha | 7.00 (0.75) | 8.31 (1.36) | <0.001 | 4 |
| ITGAV | 3.38 (0.27) | 3.05 (0.34) | <0.001 | 5 |
| DNER | 8.03 (0.37) | 7.57 (0.48) | <0.001 | 6 |
| IL6 | 4.07 (1.31) | 5.35 (1.40) | <0.001 | 7 |
| CDCP1 | 3.55 (0.72) | 4.26 (0.81) | <0.001 | 8 |
| VEGFR-2 | 7.13 (0.28) | 6.82 (0.35) | 0.001 | 9 |
| IL10 | 3.02 (0.61) | 3.76 (0.88) | 0.001 | 10 |
| CXCL13 | 8.38 (0.80) | 9.10 (0.84) | 0.001 | 11 |
| WISP-1 | 4.48 (0.60) | 5.16 (0.81) | 0.001 | 12 |
| TNFRSF6B | 4.32 (0.71) | 5.03 (0.85) | 0.001 | 13 |
| CTSV | 3.76 (0.71) | 3.14 (0.71) | 0.001 | 14 |
| CCL23 | 10.04 (0.51) | 10.48 (0.52) | 0.001 | 15 |
| CXCL1 | 7.66 (1.34) | 8.67 (1.22) | 0.002 | 16 |
| SCF | 9.69 (0.52) | 9.09 (0.79) | 0.002 | 17 |
| TNFRSF4 | 3.32 (0.60) | 3.85 (0.69) | 0.002 | 18 |
| CXCL11 | 8.10 (1.27) | 9.29 (1.58) | 0.002 | 19 |
| VEGFA | 9.88 (0.56) | 10.45 (0.79) | 0.003 | 20 |
| CD40 | 9.93 (0.68) | 10.55 (0.88) | 0.005 | 21 |
| IL-10RB | 6.74 (0.34) | 7.04 (0.42) | 0.005 | 22 |
| CSF-1 | 8.17 (0.30) | 8.38 (0.28) | 0.005 | 23 |
| TNFSF14 | 4.53 (0.77) | 5.26 (1.08) | 0.005 | 24 |
| CCL3 | 4.91 (0.70) | 5.54 (0.92) | 0.005 | 25 |
| SCAMP3 | 3.03 (1.82) | 4.61 (2.33) | 0.006 | 26 |
| CXCL6 | 7.53 (1.29) | 8.50 (1.42) | 0.006 | 27 |
| ABL1 | 2.79 (1.63) | 4.32 (2.37) | 0.008 | 28 |
| TXLNA | 4.01 (1.92) | 5.58 (2.42) | 0.008 | 29 |
| IL-17C | 1.48 (0.63) | 2.30 (1.32) | 0.008 | 30 |
| PVRL4 | 6.10 (0.65) | 6.75 (1.03) | 0.008 | 31 |
| IL8 | 6.26 (1.26) | 7.04 (1.13) | 0.008 | 32 |
| IL-18R1 | 7.05 (0.47) | 7.41 (0.55) | 0.008 | 33 |
| RSPO3 | 3.81 (0.61) | 4.37 (0.89) | 0.008 | 34 |
| TFPI-2 | 7.78 (0.63) | 8.31 (0.82) | 0.008 | 35 |
| MCP-1 | 10.14 (0.55) | 10.58 (0.69) | 0.008 | 36 |
| CXCL9 | 7.70 (1.24) | 8.46 (1.13) | 0.008 | 37 |
| ICOSLG | 3.90 (0.29) | 3.65 (0.39) | 0.008 | 38 |
| PD-L1 | 3.79 (0.45) | 4.18 (0.61) | 0.008 | 39 |
| TNFRSF9 | 6.20 (0.63) | 6.66 (0.73) | 0.008 | 40 |
| IL-15RA | 0.35 (0.18) | 0.50 (0.24) | 0.008 | 41 |
| DKN1A | 2.36 (2.33) | 4.19 (2.95) | 0.009 | 42 |
| LYN | 1.17 (1.11) | 1.94 (1.27) | 0.011 | 43 |
| LYPD3 | 4.07 (0.48) | 3.70 (0.61) | 0.011 | 44 |
| FASLG | 8.90 (0.57) | 8.54 (0.57) | 0.012 | 45 |
| ADAM-TS 15 | 4.33 (0.58) | 4.76 (0.71) | 0.012 | 46 |
| OPG | 10.66 (0.30) | 10.94 (0.48) | 0.012 | 47 |
| ESM-1 | 8.92 (0.48) | 9.25 (0.56) | 0.014 | 48 |
| MMP-1 | 12.32 (1.37) | 13.36 (1.84) | 0.018 | 49 |
| EGF | 6.25 (2.23) | 7.74 (2.62) | 0.018 | 50 |
| SYND1 | 6.46 (0.67) | 6.94 (0.85) | 0.018 | 51 |
| MSLN | 2.18 (0.88) | 2.89 (1.33) | 0.021 | 52 |
| IL7 | 3.59 (1.21) | 4.35 (1.39) | 0.023 | 53 |
| LAP TGF-beta-1 | 7.53 (0.67) | 8.00 (0.88) | 0.023 | 54 |
| TNFSF13 | 8.39 (0.39) | 8.65 (0.47) | 0.025 | 55 |
| VIM | 3.47 (1.32) | 4.07 (1.01) | 0.025 | 56 |
| IL-12B | 4.38 (0.70) | 4.80 (0.77) | 0.027 | 57 |
| SEZ6L | 5.33 (0.40) | 5.06 (0.51) | 0.027 | 58 |
| hK11 | 5.79 (0.77) | 6.35 (1.07) | 0.027 | 59 |
| SIRT2 | 3.38 (1.99) | 4.66 (2.46) | 0.028 | 60 |
| EPHA2 | 1.46 (0.46) | 1.79 (0.64) | 0.028 | 61 |
| 4E-BP1 | 8.82 (1.31) | 9.52 (1.29) | 0.028 | 62 |
| TNFRSF19 | 4.06 (0.49) | 4.46 (0.77) | 0.028 | 63 |
| FURIN | 4.02 (0.46) | 4.29 (0.50) | 0.029 | 64 |
| CCL4 | 6.44 (0.60) | 6.91 (0.93) | 0.029 | 65 |
| FADD | 0.75 (1.22) | 1.52 (1.51) | 0.029 | 66 |
| AXIN1 | 3.55 (2.20) | 5.03 (2.93) | 0.029 | 67 |
| MCP-4 | 3.74 (1.10) | 4.31 (1.08) | 0.029 | 68 |
| CEACAM1 | 7.56 (0.17) | 7.43 (0.23) | 0.029 | 69 |
| CD27 | 7.85 (0.43) | 8.14 (0.58) | 0.029 | 70 |
| HGF | 8.39 (0.54) | 8.78 (0.79) | 0.031 | 71 |
| FGF-21 | 5.82 (1.52) | 6.69 (1.72) | 0.034 | 72 |
| STAMPB | 4.90 (1.67) | 5.96 (2.15) | 0.034 | 73 |
| MetAP 2 | 4.18 (1.06) | 4.79 (1.25) | 0.035 | 74 |
| CASP-8 | 1.19 (0.76) | 1.69 (1.04) | 0.038 | 75 |
| TNFB | 3.92 (0.39) | 3.60 (0.72) | 0.043 | 76 |
| CCL20 | 5.59 (1.22) | 6.19 (1.28) | 0.049 | 77 |
| ST1A1 | 1.16 (1.29) | 1.94 (1.69) | 0.049 | 78 |
a p-values adjusted with FDR.