Table 6. Normalized protein expression (NPX) values.
Benign tumors vs. borderline + cancer, p < 0.05.
| Benign | Borderline + Cancer | |||
|---|---|---|---|---|
| Protein | Mean (sd) | Mean (sd) | Adj. p-vala | Rank |
| WFDC2 | 7.35 (0.71) | 8.15 (0.75) | <0.001 | 1 |
| MUC-16 | 4.67 (1.93) | 6.26 (1.54) | <0.001 | 2 |
| ITGAV | 3.37 (0.27) | 3.08 (0.35) | 0.002 | 3 |
| MK | 7.11 (0.88) | 7.86 (0.92) | 0.002 | 4 |
| VEGFR-2 | 7.13 (0.28) | 6.85 (0.35) | 0.002 | 5 |
| FR-alpha | 6.99 (0.75) | 8.05 (1.41) | 0.002 | 6 |
| DNER | 8.01 (0.37) | 7.63 (0.49) | 0.002 | 7 |
| CTSV | 3.75 (0.70) | 3.19 (0.70) | 0.002 | 8 |
| CXCL13 | 8.37 (0.78) | 9.02 (0.82) | 0.002 | 9 |
| WISP-1 | 4.45 (0.61) | 5.06 (0.81) | 0.003 | 10 |
| IL6 | 4.03 (1.31) | 5.15 (1.51) | 0.003 | 11 |
| CXCL1 | 7.56 (1.42) | 8.55 (1.30) | 0.004 | 12 |
| CCL23 | 10.03 (0.51) | 10.42 (0.54) | 0.004 | 13 |
| CXCL11 | 8.06 (1.27) | 9.12 (1.55) | 0.007 | 14 |
| TNFRSF6B | 4.33 (0.70) | 4.90 (0.86) | 0.008 | 15 |
| CDCP1 | 3.52 (0.72) | 4.09 (0.88) | 0.010 | 16 |
| IL10 | 3.03 (0.60) | 3.61 (0.92) | 0.011 | 17 |
| IL-10RB | 6.73 (0.34) | 7.00 (0.42) | 0.012 | 18 |
| SCF | 9.67 (0.51) | 9.19 (0.78) | 0.012 | 19 |
| VEGFA | 9.85 (0.58) | 10.34 (0.80) | 0.013 | 20 |
| CD40 | 9.91 (0.69) | 10.47 (0.90) | 0.014 | 21 |
| CXCL6 | 7.45 (1.32) | 8.37 (1.46) | 0.014 | 22 |
| ICOSLG | 3.90 (0.29) | 3.67 (0.39) | 0.015 | 23 |
| IL-18R1 | 7.07 (0.47) | 7.38 (0.51) | 0.015 | 24 |
| IL-17C | 1.44 (0.66) | 2.17 (1.26) | 0.015 | 25 |
| CCL3 | 4.88 (0.70) | 5.45 (0.96) | 0.015 | 26 |
| PD-L1 | 3.78 (0.45) | 4.13 (0.60) | 0.015 | 27 |
| MMP-1 | 12.26 (1.39) | 13.30 (1.76) | 0.015 | 28 |
| TNFRSF4 | 3.34 (0.60) | 3.75 (0.69) | 0.015 | 29 |
| ABL1 | 2.76 (1.62) | 4.16 (2.42) | 0.015 | 30 |
| LYPD3 | 4.08 (0.47) | 3.73 (0.58) | 0.015 | 31 |
| SCAMP3 | 2.98 (1.80) | 4.39 (2.40) | 0.015 | 32 |
| IL-15RA | 0.34 (0.18) | 0.48 (0.24) | 0.015 | 33 |
| TNFSF14 | 4.52 (0.76) | 5.15 (1.13) | 0.018 | 34 |
| TXLNA | 3.96 (1.91) | 5.36 (2.46) | 0.018 | 35 |
| CSF-1 | 8.16 (0.30) | 8.33 (0.29) | 0.018 | 36 |
| IL8 | 6.21 (1.28) | 6.90 (1.17) | 0.019 | 37 |
| DKN1A | 2.30 (2.31) | 3.96 (2.97) | 0.019 | 38 |
| RSPO3 | 3.80 (0.61) | 4.28 (0.86) | 0.019 | 39 |
| LYN | 1.14 (1.10) | 1.85 (1.28) | 0.024 | 40 |
| MCP-1 | 10.12 (0.56) | 10.49 (0.69) | 0.024 | 41 |
| LAP TGF-beta-1 | 7.49 (0.69) | 7.96 (0.87) | 0.025 | 42 |
| PVRL4 | 6.09 (0.63) | 6.63 (1.01) | 0.025 | 43 |
| TFPI-2 | 7.78 (0.61) | 8.22 (0.81) | 0.026 | 44 |
| IL7 | 3.53 (1.23) | 4.27 (1.38) | 0.026 | 45 |
| MCP-4 | 3.69 (1.12) | 4.29 (1.11) | 0.026 | 46 |
| EGF | 6.18 (2.23) | 7.57 (2.62) | 0.026 | 47 |
| CXCL9 | 7.68 (1.23) | 8.31 (1.17) | 0.029 | 48 |
| CEACAM1 | 7.55 (0.17) | 7.43 (0.23) | 0.030 | 49 |
| ADAM-TS 15 | 4.32 (0.58) | 4.68 (0.69) | 0.033 | 50 |
| FASLG | 8.91 (0.57) | 8.61 (0.58) | 0.033 | 51 |
| OPG | 10.65 (0.31) | 10.89 (0.49) | 0.036 | 52 |
| CCL4 | 6.42 (0.61) | 6.87 (0.95) | 0.041 | 53 |
| CXCL5 | 9.69 (2.15) | 10.70 (2.02) | 0.046 | 54 |
| IL-12B | 4.40 (0.69) | 4.76 (0.74) | 0.046 | 55 |
| ESM-1 | 8.92 (0.47) | 9.19 (0.57) | 0.047 | 56 |
| SIRT2 | 3.30 (2.00) | 4.50 (2.53) | 0.048 | 57 |
a p-values adjusted with FDR.