Figure - PMC

Skip to main content

View full-text article in PMC

. Author manuscript; available in PMC: 2021 Jun 1.

Published in final edited form as: J Trauma Acute Care Surg. 2020 Jun;88(6):742–751. doi: 10.1097/TA.0000000000002681

Figure 1. — (Panels A-D). Filtering and validating methodology to identify activated platelet-specific spliced RNA transcripts discovered in CFP from isolated severe fatal traumatic brain injury patients. Publicly available RNA sequencing data sets^22,28,29 were used to generate lists of activated platelet-specific spliced RNA transcripts discoverable in CFP and applied to isolated severe fTBI patient CFP sequencing data. Panel A: RNA transcripts discoverable in CFP (1427 RNA splice-form variant transcripts). Panel B: nonactivated platelet-specific RNA transcripts discoverable in CFP (685 platelet-specific RNA transcripts). Panel C: activated platelet-specific RNA transcripts discoverable in CFP (780 activated platelet-specific RNA splice-form variant transcripts). Panel D: activated platelet-specific spliced RNA transcripts discoverable in CFP from isolated severe fTBI patients (42 spliced RNA transcripts in 34 genes).

Figure 1. — (Panels A-D). Filtering and validating methodology to identify activated platelet-specific spliced RNA transcripts discovered in CFP from isolated severe fatal traumatic brain injury patients. Publicly available RNA sequencing data sets^22,28,29 were used to generate lists of activated platelet-specific spliced RNA transcripts discoverable in CFP and applied to isolated severe fTBI patient CFP sequencing data. Panel A: RNA transcripts discoverable in CFP (1427 RNA splice-form variant transcripts). Panel B: nonactivated platelet-specific RNA transcripts discoverable in CFP (685 platelet-specific RNA transcripts). Panel C: activated platelet-specific RNA transcripts discoverable in CFP (780 activated platelet-specific RNA splice-form variant transcripts). Panel D: activated platelet-specific spliced RNA transcripts discoverable in CFP from isolated severe fTBI patients (42 spliced RNA transcripts in 34 genes).