Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Flowchart for calculation of quality-adjusted time without symptoms or toxicity (TWiST; Q-TWiST). The mean time with symptoms of disease (REL state) was not included in these analyses because ARIEL3 OS data were not mature at the time of this analysis. AEs, adverse events; OS, overall survival; PFS, progression-free survival; TOX, time with toxicity of treatment.
