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. Author manuscript; available in PMC: 2021 Mar 19.
Published in final edited form as: Mol Cell. 2020 Jan 17;77(6):1265–1278.e7. doi: 10.1016/j.molcel.2019.12.019

Fig. 1. Overall structure of the SUZ12(N)-RBBP4-PHF19(RC)-JARID2(TR) heterotetrameric complex in the dimeric state.

Fig. 1

(A) Domain structures of the proteins in the crystal. ZnB, Zinc-finger Binding; WDB1, WD40-Binding 1; Zn, Zinc-finger; WDB2, WD40-Binding 2; NT, N-Terminal; DS, Dimer Stabilization; SC, Short Connecting; C2B, C2-Binding; CT, C-Terminal; TR, Transrepression. C2 and βL7 are not abbreviated names.

(B) Cartoon representation of the dimeric complex in Top View. Disordered protein loops are displayed as dotted lines. Hinge loops that connect to the C2 domains are indicated by black arrows. The second protomer of the dimer is labeled with a prime symbol.

(C) Surface representation of the dimeric complex in Side View. The rotational matrix that relates the Top View and Side View is indicated.

See also Fig. S1.