TABLE 1.
Country IOC Code |
N | Age range | Dataset | Relatives | FHCMen | FHCWomen | OR | CI95% | |
---|---|---|---|---|---|---|---|---|---|
Pinsky et al (2003) 8 | USA | 149 332 | 55‐74 | PLCO Trial | FDR | 53.1 | 61.0 | 0.72 | 0.71‐0.74 |
McQueen et al (2006) 5 | USA | 2686 | ≥50 | HINTS 1 | CFM | 61.3 | 70.3 | 0.72 | 0.61‐0.85 |
Townsend et al (2013) 17 | USA | 30 260 | 18‐64 | 2005 CHIS | FDR, SDR | 28.7 | 34.2 | 0.77 | 0.74‐0.81 |
Bostean et al (2013) 14 | USA | 30 520 | 40‐75 | 2009 CHIS | FDR | 50.0 | 54.4 | 0.84 | 0.80‐0.88 |
Sieverding et al (2008) 7 | GER | 15 810 | 50‐70 | 2004 HCAP | GP, P, S | 39.1 | 47.9 | 0.70 | 0.66‐0.74 |
Hidalgo et al (2015) 15 | ESP | 666 | ≥ 50 | bespoke survey | FDR | 42.3 | 52.7 | 0.66 | 0.48‐0.90 |
Hwang et al (2019) 13 | KOR | 166 810 | 40‐79 | HEXA | FDR | 25.4 | 28.1 | 0.87 | 0.85‐0.89 |
Choi et al (2013) 18 | CHN | 2004 | ≥50 | bespoke survey | AFM | 21.7 | 22.1 | 0.98 | 0.79‐1.21 |
Moghimi‐Dehkordi et al (2012) 16 | IRI | 6453 | ≥20 | bespoke survey | FDR, SDR | 37.1 | 27.7 | 1.54 | 1.39‐1.71 |
Abbreviations: 95% CI, 95%‐Confidence Interval; AFM, Any Family Member; C, Children; CFM, Close Family Members; CHIS, California Health Interview Survey; FDR, First Degree Relatives; FHCMen/FHCWomen, percentage of men/women indicating a positive Family History of Cancer (FHC); GP, Grandparents; HCAP, Health Care Access Panel; HEXA, Health Examinees Study; HINTS 1, Health Information National Trends Survey (First Iteration, 2003); N, Number of study participants; OR, Odds Ratio (men/women); P, Parents; PLCO Trial, Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial; S, Siblings; SDR, Second Degree Relatives.