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. Author manuscript; available in PMC: 2021 Oct 1.
Published in final edited form as: Biol Blood Marrow Transplant. 2020 Jul 9;26(10):1876–1885. doi: 10.1016/j.bbmt.2020.07.005

Table 3.

Adjusted (for age) outcomes after allogeneic transplant receiving ixazomib plus standard graft-versus-host disease (GVHD) prophylaxis on the study.

Outcomes Phase II MRD (n=25) Probability (95% CI) Phase II MUD (n=26) Probability (95% CI)
Chronic GVHD, 1 year 36% (19-54) 39% (21-56)
Moderate/Severe Chronic GVHD, 1 year 28% (13-46) 27% (12-44)
Acute GVHD, grade II-IV, 100 days 20% (8-37) 15% (5-31)
Acute GVHD, grade III-IV, 100 days 8% (1-22) 12% (3-26)
Acute GVHD, grade II-IV, 180 days 28% (13-46) 23% (10-40)
Acute GVHD, grade III-IV, 180 days 8% (1-22) 15% (5-31)
Non-relapse mortality, 1 year 0% 4% (0-16)
Relapse, 1 year 20% (8-37) 35% (18-52)
Relapse-free survival, 1 year 80% (58-91) 62% (40-77)
Overall survival, 1 year 92% (72-98) 89% (68-96)