Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Oct 19;76(17):2011–2023. doi: 10.1016/j.jacc.2020.08.059

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 by the American College of Cardiology Foundation. Published by Elsevier.

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

PMC Copyright notice

Central Illustration — Overview of the Mechanisms of Myocardial Injury in Patients With Coronavirus Disease 2019

Myocardial injury in the setting of COVID-19 is frequent and associated with poor prognosis. The mechanisms through which COVID-19 can cause myocardial injury are heterogeneous and include oxygen supply–demand imbalance, microvascular and macrovascular thrombosis, inflammation-related injury, stress-induced cardiomyopathy, and direct viral invasion of the myocardium.

COVID-19 = coronavirus disease 2019; IL = interleukin; MI = myocardial infarction; SARS-CoV-2 = severe acute respiratory syndrome coronavirus 2; TNF = tumor necrosis factor.