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. 2020 Oct 6;16(2):156–160. doi: 10.17925/EE.2020.16.2.156

Table 1: Comparison of demographic, anthropometric and clinical parameters between euthyroid patients with PCOS and those with subclinical hypothyroidism and PCOS.

Variables All subjects (n=465) Euthyroid (n=415) SCH (n=50) p value
Age, mean years ± SD 22.52 ± 5.38 22.37 ± 5.38 23.76 ± 5.27 0.085
Age at onset of PCOS symptoms, mean years ± SD 17.79 ± 5.20 17.64 ± 5.09 19.04 ± 5.91 0.073
Married, % 47.7 46.7 56.0 0.233
Menstrual irregularity, % 92.9 92.8 94.0 1.000
Hirsutism, % 74.4 76.4 58.0 0.009
Modified FG score, mean ± SD 11 ± 6 11 ± 6 9 ± 5 0.003
Acne, % 18.9 19.0 18.0 1.000
Gained weight*, % 58.5 56.9 72.0 0.048
Subfertility,† (in married patients, n=221), % 36.7 36.3 39.3 0.834
Family history of thyroid disease, % 2.8 2.7 4.0 0.640
BMI, mean kg/m2 ± SD 26.63 ± 5.12 26.53 ± 5.14 27.39 ± 4.93 0.264
Overweight/obese, % 76.8 75.2 90.0 0.020
WC, mean cm ± SD 87.57 ± 11.70 87.34 ± 11.87 89.54 ± 10.09 0.209
Central obesity, % 75.3 73.7 88.0 0.025
Acanthosis nigricans, % 80.9 80.2 86.0 0.446
Goiter, % 56.1 53.3 80.0 <0.001
Systolic BP, mean mmHg ± SD 115 ± 12 112 ± 12 118 ± 13 0.098
Diastolic BP, mean mmHg ± SD 75 ± 8 75 ± 9 75 ± 8 0.553
Pre-HTN/HTN, % 24.7 23.9 32.0 0.225

p value by Student’s t-test or Chi-square test as applicable.

*In the 6 months prior to PCOS diagnosis.

†Failure to conceive after 1 year of unprotected regular (2 x week) sexual intercourse; the male partner was fertile evidenced by a normal semen analysis report.

BMI = body mass index; BP = blood pressure; FG = Ferriman–Gallwey;

HTN = hypertension; PCOS = polycystic ovary syndrome; SCH = subclinical hypothyroidism; SD = standard deviation; WC = waist circumference.