Table 1. Characteristics of the study patients (N = 140) at baseline and outcomes.a .
Characteristic | Result | |
---|---|---|
Male, n (%) | 86/140 (61.4) | |
Age, years | 71 [58.5-80.0] | |
Age bracket, n (%) | < 50 years | 18/140 (12.9) |
50-75 years | 72/140 (51.4) | |
> 75 years | 50/140 (35.7) | |
Smoking status, n (%) | Never smoker | 100/139 (71.9) |
Current smoker | 26/139 (18.7) | |
Former smoker | 13/139 (9.4) | |
RT-PCR, n (%) | 139/139 (100.0) | |
Comorbidities | ||
Presence of comorbidity, n (%) | 116/139 (83.5) | |
BMI > 30 kg/m2, n (%) | 23/139 (16.6) | |
COPD, n (%) | 15/139 (10.8) | |
Diabetes, n (%) | 38/139 (27.3) | |
Hypertension, n (%) | 79/139 (56.8) | |
CHD, n (%) | 29/139 (20.9) | |
Liver disease, n (%) | 6/139 (4.3) | |
Cancer, n (%) | 24/139 (17.3) | |
Kidney disease, n (%) | 23/138 (16.7) | |
Immunodeficiency, n (%) | 0/139 (0.0) | |
Symptoms | ||
Presence of a symptom, n (%) | 132/138 (95.7) | |
Fever, n (%) | 121/139 (87.1) | |
Cough, n (%) | 69/138 (50.0) | |
Sputum, n (%) | 17/138 (12.3) | |
Dyspnea, n (%) | 79/139 (56.8) | |
Baseline chest X-rays | ||
Time from the onset of symptoms to performing X-ray, days | 4 [1-8] | |
Chest X-ray score, n (%) | No lung involvement | 7/140 (5.0) |
Lung involvement, 1-25% | 58/140 (41.4) | |
Lung involvement, 26-50% | 31/140 (22.1) | |
Lung involvement, 51-75% | 26/140 (18.6) | |
Lung involvement, 76-100% | 18/140 (12.9) | |
Baseline laboratory data | ||
WBC/mL | 5,920 [4,145-8,850] | |
CRP, mg/L | 29.6 [11.6-101.4] | |
pH | 7.45 ± 0.04 | |
PaO2, mmHg | 62.7 [53.4-76.6] | |
PaCO2, mmHg | 34.5 ± 5.2 | |
SaO2, % | 94.7 [91-96] | |
HCO3, mmol/L | 24.5 ± 2.7 | |
PaO2/FiO2 ratio | 279.0 [173.5-333.5] | |
Mild hypoxia, n (%) | 25/97 (25.8) | |
Moderate hypoxia, n (%) | 25/97 (25.8) | |
Severe hypoxia, n (%) | 13/97 (13.4) | |
Outcome | ||
Oxygen therapy, n (%) | 96/140 (68.6) | |
NIV, n (%) | 38/140 (27.1) | |
Intubation, n (%) | 28/140 (20.0) | |
Death, n (%) | 28/138 (20.9) | |
Recovery, n (%) | 41/113 (36.3) | |
Patient management, n (%) | Discharge | 9/115 (7.8) |
Hospitalization | 66/115 (57.4) | |
ICU | 40/115 (34.8) |
BMI: body mass index; CHD: coronary heart disease; WBC: white blood cell; CRP: C-reactive protein; and NIV: noninvasive ventilation. aValues expressed as mean ± SD or median [interquartile range], except where otherwise indicated.