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. 2020 Jul 19;5(10):1643–1650. doi: 10.1016/j.ekir.2020.07.012

Figure 1.

Figure 1

Graph of estimated prevalence of IgA nephropathy (IgAN) in different mixture (hematuria, hypertension [HTN], microalbuminuria [micalb]) (with 95% confidence intervals represented by error bars). Controls: UK Biobank (UKBB) healthy individuals (without IgAN, hypertension, diabetes, albuminuria, renal disease). IgAN-related phenotypes: hematuria, hypertension, microalbuminuria. Cases: IgAN cases from UKBB and UK Glomerulonephritis DNA Bank (UKGDB) combined. Red numbers represent the genetic risk score (GRS) of phenotype that could be explained by IgAN calculated using the following formula: Proportion = (phenotype GRS – control GRS) / (IgAN-GRS – control GRS).