Table 5.
Oncologic outcomes according to clinical and treatment factors
Factor | n | 2-Year PC (%) | p | 2-Year LC (%) | p | 2-Year PFS (%) | p |
---|---|---|---|---|---|---|---|
Concurrent chemotherapy | |||||||
Yes | 29 | 83 | 0.927 | 86 | 0.724 | 76 | 0.851 |
No | 11 | 82 | 82 | 73 | |||
Pretreatment tumor diametera | |||||||
< 40 mm | 11 | 100 | 0.081 | 100 | 0.109 | 91 | 0.17 |
≥ 40 mm | 29 | 76 | 79 | 69 | |||
Pre-ICBT tumor diametera | |||||||
< 40 mm | 24 | 96 | 0.004 | 96 | 0.013 | 92 | 0.001 |
≥ 40 mm | 15 | 60 | 67 | 47 | |||
HR-CTV | |||||||
< 40 cm3 | 22 | 96 | 0.03 | 96 | 0.077 | 96 | 0.001 |
≥ 40 cm3 | 17 | 71 | 77 | 53 | |||
Total HR-CTV D90 | |||||||
≥ 70 Gy | 29 | 90 | 0.044 | 93 | 0.018 | 83 | 0.044 |
< 70 Gy | 11 | 64 | 64 | 55 | |||
Overall treatment time | |||||||
< 57 days | 28 | 93 | 0.009 | 93 | 0.035 | 89 | 0.001 |
≥ 57 days | 12 | 58 | 67 | 42 |
PC pelvic control, LC local control, PFS progression-free survival, ICBT intracavitary brachytherapy, HR-CTV high-risk clinical target volume
aAssessed by MRI T2WI