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. 2020 Oct 19;10:17597. doi: 10.1038/s41598-020-74483-1

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Comparison of transcriptional profiles of the FFPE cohort compared to TCGA samples. Per-gene mean expression comparison between our FFPE and TCGA cohorts before (A) and after (B) the mapping of TCGA into FFPE RNA-Seq space is shown. (C) Pathway MSigDB enrichments for each of the cancer type, as well as FF/OCT samples, vs. TCGA of matched cancer type were computed using top differential genes; enrichment strength is based on FWER p-value.