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. Author manuscript; available in PMC: 2021 Dec 1.
Published in final edited form as: J Allergy Clin Immunol. 2020 Apr 15;146(6):1406–1418.e7. doi: 10.1016/j.jaci.2020.03.032

Figure 2. Acute TSLP mediated allergic airway inflammation requires T cells and signaling molecule STAT6.

Figure 2.

Mice were treated with TSLP/OVA (T/O) or PBS (CTR) every 3 days as described in Fig. 1a, the lungs were harvested at d7 and airway eosinophilia was determined by flow cytometry. Pulmonary eosinophil infiltration in the lungs of (a) wild type C57BL/6 mice pretreated with anti-CD4 (GK1.5) or control (Rat IgG) antibodies (n=4–6), and (b) STAT6 deficient (Balb/c background) and wild type Balb/c mice (n=4–5). Data are representative of at least two independent experiments. ** p<0.01, *** p<0.001, ****p<0.0001. (a) and (b), p-value by two-way ANOVA.