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. Author manuscript; available in PMC: 2021 Nov 1.
Published in final edited form as: Radiother Oncol. 2020 Apr 20;152:133–145. doi: 10.1016/j.radonc.2020.04.018

Figure 8.

Figure 8.

Biomarker panel predictive of radiation induced cardiac toxicity 2 weeks post-RT. Panel A. ROC curve of a six-metabolite biomarker SVM panel with AUC = 0.938 (0.782-1); six-metabolite plus BNP biomarker SVM panel with AUC = 0.955 (0.857-1). Panel B. Uncertainty matrix showing distribution of patients based on the biomarker pane. Panel C. Pattern of abundance for the six-metabolite panel in patients who developed cardiac toxicity as compared to those who did not. Panel D. The linear SVM model that distinguishes the two patient groups.