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. 2020 Oct 19;11:5268. doi: 10.1038/s41467-020-19052-w

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — a A sunburst plot visualizing the functional classification of the glycoproteins that bear significantly changed glycoforms upon 2FF treatment. Significant regulation is defined using Z score >2 or <−2. b, c Visualization of all quantified glycosylation sites (N) on PTPRC (b) and CD79b (c) under 2FF treatment with specified residue number and number of quantified glycoforms in bracket. A glycosite that showed a significantly changed glycosylation level is marked in green. Regulated glycoforms are shown with their glycan compositions presented as the numbers of Hex, HexNAc, NeuAc, and Fucose (dashed box). Determined fold changes of glycoforms upon 2FF treatment with various concentrations are shown by color-coded rectangles. Source data are provided in supplementary data 5 and Source Data file.