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. 2020 Oct 19;11:5281. doi: 10.1038/s41467-020-19006-2

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — a MDS of time-point specific expression profiles based on MT/MG ratios or evidence at the MP level. Colors indicate FunC assignment of the individual rMAGs. Point shape represents cluster assignment based on automated clustering of the embedded points. Ellipses containing 95% of cluster-assigned data points are shown. Points size represents the average MT/MG depth ratios of the individual rMAGs. The amounts of variance explained by the first two dimensions are shown on the respective axes. b Mean MT/MG depth ratios over all time-points are shown per condition for 78 rMAGs (boxplots show: center line, median; box limits, upper and lower quartiles; whiskers, 1.5× interquartile range; Each group of boxplots corresponds to a group of rMAGs (FunC-1 n = 24, FunC-2 n = 23, FunC-3 n = 19, FunC-4 n = 12), each boxplot represents an independent experiment.). c Mean MT/MG depth ratios grouped according to class-level taxonomic assignment of the rMAGs with the number of rMAGs for each group are shown in the top of the plot (n). Source data are provided as a Source Data file.