. Author manuscript; available in PMC: 2021 Sep 1.

Published in final edited form as: Arthritis Rheumatol. 2020 Aug 6;72(9):1483–1492. doi: 10.1002/art.41291

Table 1:

Association of the weighted genetic risk score for RA with cardiometabolic and autoimmune phenotypes

Phenotype	phecode	# cases	# controls	OR [95%CI]	P-value
Atrial fibrillation	427.21	5195	14453	0.98 [0.94, 1.02]	0.249
Ischemic stroke	433.21	1399	23097	1.02 [0.97, 1.08]	0.392
Coronary atherosclerosis	411.4	8720	16746	0.99 [0.96, 1.02]	0.489
Type 2 diabetes	250.2	6309	19612	1.02 [0.98, 1.05]	0.252
Essential hypertension	401.1	16488	11767	0.98 [0.95, 1.01]	0.131
Chronic renal failure	585.3	3486	21257	1.01 [0.97, 1.05]	0.580
Hyperlipidemia	272.13	587.6	15039	1.00 [0.97, 1.03]	0.988
Obesity	278.1	4438	22965	0.99 [0.96, 1.02]	0.621
Type 1 diabetes	250.1	1456	19571	1.10 [1.04, 1.16]	9.82×10⁻⁴
Multiple sclerosis	335	1009	21542	0.82 [0.77, 0.88]	1.73×10⁻⁸