TABLE 1.
Correlation of CRY1 and/ or CRY2 expression with human tumor phenotype (vs normal control tissue) and with survival outcome
| Cancer type | CRY1 | CRY2 | References |
|---|---|---|---|
| Gastric | Increased; associated with advanced stage NC | NC Decreased |
125 8 |
| Thyroid | NC Decreased |
Decreased Decreased |
126 8 |
| Glioma | NC | Increased Associated with poor outcome |
127 8 |
| Skin | Decreased NC |
Decreased |
128 42 |
| Ovarian | Increased; associated with improved survival |
Decreased | 129 |
| Pancreas (PDAC) | Decreased | Decreased | 130 |
| Colorectal | NC Decreased NC |
Decreased Decreased Decreased |
131 132 8 |
| Lung | Decreased (LUSC and LUAD) Decreased |
Decreased (LUSC and LUAD) Decreased |
8 42 |
| Kidney | Decreased in KICH | Increased (KICH), Decreased (KIRP); low expression associated with poor outcomes (KIRP, KIRC) | 8 |
| Breast | NC NC |
Decreased; alters subtype Decreased |
8 42 |
| Liver | NC | NC; low expression associated with worse outcome | 8 |
| Head and Neck | NC | Decreased | 8 |
| Bladder | NC | Decreased | 8 |
| Esophagus | Decreased | Decreased | 8 |
| Prostate | NC | NC | 8 |
| Bone | NC | Decreased | 42 |
Abbreviations: KICH, kidney chromophobe; KIRC, kidney renal clear cell carcinoma; KIRP, kidney renal papillary carcinoma; LUAD, lung adenocarcinoma; LUSC, lung squamous cell carcinoma; NC, no change; PDAC, pancreatic ductal adenocarcinoma.