Extended Data Table 5 |.
Conservation of B- and T-cell epitopes in the E1 fusion protein of the rubella wild-type virus 1B, ruhugu virus, and rustrela virus.
| Epitope | Rubella virus (JN635282) | Ruhugu virus (MN547623) | Rustrela virus (MN552442) | |
|---|---|---|---|---|
| Linear, neutralizing B-cell epitopes | NT1:E11221–239 | LGSPNCHGPDWASPVCQRHS | VGLPNCHGPDWASPVCQQHS | VPAPDCFGPAWASPVCARHM |
| NT2: E1245–251 | LVGATPE | LTGVPPE | LTGATPG | |
| NT3 :E1260–266 | ADDPLLR | ADDPRLT | ADDLGWH | |
| NT4 :E1274–285 | VWVTPVIGSQAR | VWAVAVKGTQPK | VWYQPVIGRQPR | |
| CD8+ T-cell epitopes | C9–22 | MEDLQKALEAQSRA | LADLQRLLEKQSAE | Deleted |
| C11–29 | DLQKALEAQSRALRAELAA | DLQRLLEKQSAELRAEMAR | Deleted | |
| C264–272 | RIETRSARH | KQDVKSDKV | RKEOLGATSGAA | |
Amino acid differences are in bold, insertions are underlined, and GenBank accession numbers are in parentheses.