Table 1.

Demographic Information

	Aβ−	Aβ+	All	Uncorrected p value
N (% subsample)	72	35	111	--
Sex(F)	41 (56.94%)	19 (54.29%)	61 (54.95%)	0.83
APOEε4+	13 (18.06%)	22 (62.86%)	37 (33.33%)	<0.001***
CDR = 0.5 at FTP session	5 (6.94%)	1 (2.86%)	6 (5.41%)	--
Mean (SD)
Years of education	16.28 (3.06)	16.40 (2.83)	16.35 (2.98)	0.84
FTP session MMSE	29.39 (0.88)	29.03 (1.04)	29.25 (0.96)	0.06
FTP session Logical Memory (DR)	16.40 (3.97)	15.11 (3.31)	16.05 (3.79)	0.10
Number of MRI follow-up visits	3.55 (0.67)	3.33 (0.54)	3.48 (0.63)	0.10
MRI timespan (years)	4.36 (1.15)	4.59 (0.77)	4.46 (1.05)	0.32
Retrospective MRI timespan (years)	2.38 (0.94)	2.60 (0.81)	2.43 (0.90)	0.25
Prospective MRI timespan (years)	2.10 (0.80)	1.99 (0.64)	2.03 (0.78)	0.51
IT FTP SUVr	1.43 (0.12)	1.60 (0.23)	1.49 (0.19)	<0.001***
EC FTP SUVr	1.32 (0.22)	1.64 (0.41)	1.43 (0.33)	<0.001***
PiB DVR FLR	1.17 (0.07)	1.96 (0.42)	1.43 (0.45)	--

Participant information is presented at two levels of Aβ burden as well as in the full sample. Aβ group differences were computed using two sample t-tests, chi-squared tests, and were not corrected for multiple comparisons. Four participants did not have Aβ data. FTP and PiB data shown are partial volume corrected.

Key:

^*p<0.05;

^**p<0.01;

^***p<0.001;

Abbreviations: Aβ = beta-amyloid; APOEε4 = Apolipoprotein E4 genotype; global Clinical Dementia Rating = CDR; Mini-Mental State Examination = MMSE; DR = delayed recall; FTP = flortaucipir; MRI = magnetic resonance imaging; IT = inferior temporal gyrus; EC = entorhinal cortex; SUVr = standardized uptake value ratio; PiB = Pittsburgh compound B; DVR = distribution volume ratio; FLR = frontolateral temporal/parietal-retrosplenial.