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. Author manuscript; available in PMC: 2021 Oct 1.
Published in final edited form as: Brain Behav Immun. 2020 Aug 4;89:513–517. doi: 10.1016/j.bbi.2020.07.046

Figure 1. LMX prevents anxiety-like behavior after acute restraint stress in male mice.

Figure 1.

Effects of LMX 5mg kg−1 or DMSO vehicle on behavior in male mice the Light-Dark box (a-e) and Elevated Zero Maze (f-j) immediately after restraint stress. F-scores below graphs represent main effects or interactions from Two-Way ANOVAs. p-values (above bars) represent significance levels of post-hoc Holm-Sidak pairwise comparisons. Data presented as individual values and Mean ± SEM, with number of subjects per group as follows: LD box, Vehicle-No Stress n=33, LMX-No Stress n=41, Vehicle-Stress n=34, LMX-Stress n=38. In EZM: Vehicle-No Stress n=23, LMX-No Stress n=23, Vehicle-Stress n=23, LMX-Stress n=23. Track maps show total distance traveled in the (e) LD box and (j) EZM.