Skip to main content
. Author manuscript; available in PMC: 2021 Nov 1.
Published in final edited form as: Neurobiol Dis. 2020 Aug 21;145:105058. doi: 10.1016/j.nbd.2020.105058

Figure 2.

Figure 2.

Small RNA modifications in the 15–25-nt fraction from samples of the prefrontal lobe cortex of dementia patients with and without co-occurring vascular dementia patients. (A) Increases in 2’-O-methylcytidine (Cm) 7-methylguanosine (m7G), 2’-O-methylguanosine (Gm), and 3-Methylcytidine(m3C) modifications. (B) Reductions in N2,N2 ,7-trimethylguanosine (m2,2,7G) and N2,N2-dimethylguanosine (m2,2G) modifications in the cortex of AD-w/o-VaD, AD-w-VaD, and CONT subjects (each dot in the figure represents value from one independent sample); *P < 0·05 **P <0·01 vs. CONT by Ordinary One-way ANOVA with post hoc Bonferroni correction.