Skip to main content
. Author manuscript; available in PMC: 2021 Oct 13.
Published in final edited form as: Immunity. 2020 Sep 24;53(4):852–863.e7. doi: 10.1016/j.immuni.2020.08.015

Figure 6. Epitope analysis of 1G05 and 2E01.

Figure 6.

(A) The epitope of 1G05 HC is shown as a pink-colored surface. The 1G05 HC and LC are shown as spheres in cyan and teal, respectively. (B) Epitope residues making either polar or hydrophobic interactions via side chains with 1G05 are labeled in black. Crucial contacting residues on CDRs are shown as cyan sticks.

(C, F) Conservation analysis of epitopes to 1G05 (C) and 2E01 (F) with amino acid sequences from all IBV strains [upper (C) and left (F) panels], and all IBV and IAV strains [lower (C) and right (F) panels] tested. (D) The epitopes of 2E01 HC and LC are shown as pink-colored and dark pink–colored surfaces, respectively. The 2E01 HC and LC are shown as green and dark green spheres. (E) Epitope residues making polar interactions via side chains with 2E01 are labeled in black. Crucial contacting residues on CDRs are shown as green and dark green sticks, respectively. See also Figures S6 and S7 and Tables S4 and S5.