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. Author manuscript; available in PMC: 2021 Oct 1.
Published in final edited form as: Atherosclerosis. 2020 Aug 29;311:20–29. doi: 10.1016/j.atherosclerosis.2020.08.013

Table 1.

Known ZEB2-associated GWAS SNPs that are related to the risk of CAD.

SNP ID Location on chromosome 2 Reference allele CAD risk allele Allele frequency Gene name Function Nearby gene(s) Beta of risk allele GWAS p value* References
rs2252641 145043894 T C T=0.307; C=0.693 TEX41 intron LINC01966, AC096666.1 −0.0368 5.00× 10−13 (6, 7, 14, 15)
rs1830321 145067988 C T C=0.503; T=0.497 TEX41 intron LINC01966, AC096666.1 0.033 3.19×10−8 (6, 9)
rs6740731 144513025 G A/C/T G=0.679; A=0.321 ZEB2 intron or 3’UTR ZEB2-AS1 0.0457 2.77×10−9 (6, 14, 15)
rs17678683 144528992 T G T=0.938; G=0.062 LINC01412 intron ZEB2, ZEB2-AS1 −0.0988 3.00×10−9 (6, 7, 12, 14, 15)
*

The lowest p value is provided from across all the cited CAD GWAS studies, respectively. See also Figure 1.