Table 1.
SNP ID | Location on chromosome 2 | Reference allele | CAD risk allele | Allele frequency | Gene name | Function | Nearby gene(s) | Beta of risk allele | GWAS p value* | References |
---|---|---|---|---|---|---|---|---|---|---|
rs2252641 | 145043894 | T | C | T=0.307; C=0.693 | TEX41 | intron | LINC01966, AC096666.1 | −0.0368 | 5.00× 10−13 | (6, 7, 14, 15) |
rs1830321 | 145067988 | C | T | C=0.503; T=0.497 | TEX41 | intron | LINC01966, AC096666.1 | 0.033 | 3.19×10−8 | (6, 9) |
rs6740731 | 144513025 | G | A/C/T | G=0.679; A=0.321 | ZEB2 | intron or 3’UTR | ZEB2-AS1 | 0.0457 | 2.77×10−9 | (6, 14, 15) |
rs17678683 | 144528992 | T | G | T=0.938; G=0.062 | LINC01412 | intron | ZEB2, ZEB2-AS1 | −0.0988 | 3.00×10−9 | (6, 7, 12, 14, 15) |
The lowest p value is provided from across all the cited CAD GWAS studies, respectively. See also Figure 1.