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Assessment of within-host SARS-CoV-2 diversity. (A) Total number of variants detected in each patient with mild (green) and severe (red) symptoms. (B) Number of synonymous (S) and non-synonymous (NS) mutations found within each patient of the two groups (mild vs. severe cases). P-values are indicated as follows: ****p < 0.0001, ***p < 0.001.
