. Author manuscript; available in PMC: 2021 Oct 1.

Published in final edited form as: Brain Behav Immun. 2020 Jul 24;89:380–388. doi: 10.1016/j.bbi.2020.07.024

Table 4.

Simple slope analyses for significant moderation effects

Hippocampus and CRP	Test Statistic	p-value
Low CRP	F(2, 187.61)=1.72	0.18
Mean CRP	F(2, 187.96)=0.86	0.43
High CRP	F(2, 187.80)=3.63	0.028
Contrast^*	MD(SE), [95%CI]
0 vs 1	97.32(213.51), [−323.88, 518.52]	0.65
0 vs 2+	556.19(248.34), [144.74, 967.65]	0.008
1 vs 2+	458.87(208.53), [−31.02, 948.76]	0.066
Memory and IL-1RA	Test Statistic	p-value
Low IL-1RA	χ2 (2)=6.01	0.049
Contrast^*	MD(SE), [95%CI]	p-value
0 vs 1	0.14(0.22), [−0.29, 0.57]	0.52
0 vs 2+	0.57(0.23), [0.11, 1.02]	0.014
1 vs 2+	0.42(0.28), [−0.12,0.97]	0.12
Mean IL-1RA	χ2 (2)=2.06	0.36
High IL-1RA	χ2 (2)=0.63	0.73

Indicates within model contrasts performed for significant or trending simple slope effects.

MD = estimated marginal mean difference; SE = standard error; CI = confidence interval; CRP=c-reactive protein (CRP); IL-1RA = interleukin 1 receptor antagonist. Inflammatory markers are natural log-transformed for analyses (pg/mL). Subcortical volumes are presented in mm³.