Table5.
Average adjusted 10-year change in LV structure and function associated with AVC and MAC progression: MESA.
| Progressors vs non progressors | ||
|---|---|---|
| Aortic valve calcium | Mitral annular calcium | |
| N (row %) | 210 vs 2538 | 205 vs 2543 |
| Left ventricular mass-to-volume ratio | ||
| Model 1 | 4.47 (1.30, 7.63) | 2.81 (−0.39, 6.02) |
| Model 2 | 4.47 (1.30, 7.63) | 2.81 (−0.40, 6.02) |
| Model 3 | 4.47 (1.30, 7.63) | 2.81 (−0.40, 6.01) |
| Model 4 | 4.47 (1.30, 7.63) | 2.81 (−0.40, 6.01) |
| Left ventricular mass | ||
| Model 1 | 1.21 (−0.24, 2.65) | 0.95 (−0.51, 2.41) |
| Model 2 | 1.21 (−0.23, 2.65) | 0.95 (−0.51, 2.41) |
| Model 3 | 1.21 (−0.24, 2.65) | 0.95 (−0.51, 2.41) |
| Model 4 | 1.20 (−0.24, 2.65) | 0.95 (−0.51, 2.41) |
| Left ventricular end diastolic volume | ||
| Model 1 | −0.81 (−2.59, 0.97) | 0.20 (−1.60, 2.01) |
| Model 2 | −0.81 (−2.59, 0.97) | 0.20 (−1.60, 2.01) |
| Model 3 | −0.81 (−2.59, 0.97) | 0.20 (−1.60, 2.00) |
| Model 4 | −0.81 (−2.59, 0.97) | 0.20 (−1.60, 2.00) |
| Left ventricular end systolic volume | ||
| Model 1 | 0.26 (−0.81, 1.34) | 1.41 (0.32, 2.50) |
| Model 2 | 0.26 (−0.81, 1.34) | 1.41 (0.32, 2.50) |
| Model 3 | 0.26 (−0.81, 1.34) | 1.41 (0.32, 2.50) |
| Model 4 | 0.26 (−0.81, 1.34) | 1.41 (0.32, 2.50) |
| Left ventricular stroke volume | ||
| Model 1 | −2.97 (−5.48, −0.45) | −3.12 (−5.67, −0.56) |
| Model 2 | −2.95 (−5.46, −0.43) | −3.14 (−5.69, −0.59) |
| Model 3 | −2.95 (−5.47, −0.44) | −3.15 (−5.71, −0.60) |
| Model 4 | −2.95 (−5.47, −0.44) | −3.15 (−5.71, −0.60) |
| Left ventricular ejection fraction | ||
| Model 1 | −0.84 (−1.96, 0.29) | −1.62 (−2.75, −0.48) |
| Model 2 | −0.83 (−1.96, 0.29) | −1.62 (−2.75, −0.48) |
| Model 3 | −0.84 (−1.96, 0.29) | −1.62 (−2.76, −0.48) |
| Model 4 | −0.84 (−1.96, 0.29) | −1.62 (−2.76, −0.48) |
Values in bold font are statistically significant, p<0.05
Model 1: age, race/ethnicity, sex, MESA site, & CT scanner type
Model 2: Model 1+ educational status, BMI, smoking status, pack-years of smoking, & physical activity
Model 3: Model 2 + systolic blood pressure, use of antihypertensives, use of lipid lowering medications, total cholesterol, HDL-cholesterol, diabetes status & eGFR
Model 4: Model 3 + baseline coronary calcium