Scheme 1. Total synthesis of (−)-naseseazine C (4) and (−)-iso-naseseazine C (11).
aReagents and conditions: (a), AgSbF6, EtNO2, (−)-9:(−)-10 = 1:1.4, 40%. (b) H2/Pd/C, EtOH, (80% for (−)-4 and 84% for (−)-11.
aReagents and conditions: (a), AgSbF6, EtNO2, (−)-9:(−)-10 = 1:1.4, 40%. (b) H2/Pd/C, EtOH, (80% for (−)-4 and 84% for (−)-11.