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. Author manuscript; available in PMC: 2021 Nov 1.
Published in final edited form as: Psychopharmacology (Berl). 2020 Jul 28;237(11):3337–3355. doi: 10.1007/s00213-020-05615-8

Fig. 3.

Fig. 3

Pharmacological restoration and attenuation of neophobia. a Dbh −/− mice in which central NE was restored with DOPS (n = 5) before NSF testing demonstrate significantly longer latencies to feed than Dbh −/− mice treated with vehicle (VEH; n = 6). b Dbh +/− control mice in which central NE transmission was reduced with guanfacine (n = 8) ate more rapidly than control mice treated with VEH (n = 10) in the NSF test. Error bars ± SEM, ****p < 0.0001, ***p < 0.001.