FIGURE 4.

Expression of ACE2 and TMPRSS2 in the human choroid plexus. (A) Overview and (B) high power images of sections through the human choroid plexus of the lateral ventricle, in a transmitted light DIC image (left), immunostained for ACE2 (green) and the nuclear marker DRAQ5 (blue; middle). (B) Shows representative plexus epithelial cells clearly positive for ACE2 (green). (C) Overview and (D) high power images of sections through the human choroid plexus of the lateral ventricle immunostained for TMPRSS2 (green) and the nuclear marker DRAQ5 (blue; middle). (D) Shows that TMPRSS2 has a similar distribution in choroid plexus epithelial as ACE2. All images are single optical sections (pinhole size 1 AU). Scale bars: (A,C) 20 μm; (B,D) 10 μm.