Skip to main content
. 2020 Oct 6;11:572747. doi: 10.3389/fimmu.2020.572747

Figure 1.

Figure 1

The induction of cytokines, chemokines and cell recruitment on days 4 to 9 of primary RSV infection. (A) Gene expression analysis of Tnfa, Il6, Il1b, and (B) CCL2 protein levels and Cxcl1 mRNA were determined at indicated time points in lung tissue from RSV-infected or mock infected (t=0) wt and Mavs−/− mice. Total numbers of (C) CD11b+ DCs, (D) CD103+ DCs, (E) plasmacytoid DCs (pDCs), (F) inflammatory monocytes (infMo), and (G) neutrophils in the lungs were determined by flow cytometry at indicated time points. Data are represented as mean ± SEM. Data in (A, B) are pooled from two independent experiments, n = 5–10. Data in (C–G) are representative of at least two experiments with four to five mice per group. Statistical significances of differences between indicated genotypes at each time point was determined by unpaired Student’s t test. *P < 0.05; **P < 0.01; ***P < 0.001.