Table 3.

Association between Aβ categories (low, intermediate and positive) and rsFC using linear regressions.

	Low to intermediate Aβ		Low to positive Aβ		Intermediate to positive Aβ		P-trend
	β (CI)	P	β (CI)	P	β (CI)	P
Model 1
LnDMN	0.04 (−0.01, 0.10)	0.13	−0.05 (−0.15, 0.05)	0.36	−0.09 (−0.19, 0.01)	0.08	0.12
LnFPC	0.03 (−0.03, 0.10)	0.27	0.07 (−0.04, 0.19)	0.21	0.04 (−0.08, 0.16)	0.51	0.33
LnDAN	−0.05 (−0.12, 0.02)	0.19	−0.07 (−0.20, 0.07)	0.32	−0.02 (−0.15, 0.11)	0.78	0.34
LnSAL	0.04 (−0.02, 0.10)	0.20	0.05 (−0.07, 0.16)	0.42	0.007 (−0.11, 0.12)	0.91	0.40
Model 2
LnDMN	0.02 (−0.04, 0.07)	0.57	−0.05 (−0.16, 0.05)	0.31	−0.07 (−0.17, 0.03)	0.18	0.39
LnFPC	0.01 (−0.05, 0.08)	0.69	0.05 (−0.07, 0.18)	0.40	0.04 (−0.08, 0.05)	0.69	0.69
LnDAN	−0.02 (−0.10, 0.05)	0.54	−0.03 (−0.18, 0.11)	0.64	−0.01 (−0.15, 0.13)	0.89	0.79
LnSAL	0.04 (−0.03, 0.10)	0.29	0.09 (−0.03, 0.21)	0.15	0.05 (−0.06, 0.17)	0.37	0.29

Ln, natural logarithm; Aβ, amyloid beta; SUVR, Standardized Uptake Value Ratio; rsFC, resting state functional connectivity; DMN, default mode network; FPC, fronto- parietal control; DAN, dorsal attention network; SAL, salience.

Model 1 is unadjusted. Model 2 is adjusted for age, sex, education and APOE-ε4.