Table 1.
Baseline characteristics of AIS patients stratified by SAP.
| All patients | Non-SAP (n = 868) | SAP (n = 104) | P-value | |
|---|---|---|---|---|
| Age (years), median (IQR) | 67.0 (59.0–74.0) | 66.0 (59.0–73.0) | 72.0 (65.0–80.0) | <0.001 |
| Male, n (%) | 619 (63.7%) | 553 (63.7%) | 66 (63.5%) | 0.960 |
| Current smoking, n (%) | 392 (40.3%) | 349 (59.8%) | 43 (41.3%) | 0.823 |
| Drinking, n (%) | 361 (37.1%) | 319 (63.2%) | 42 (40.4%) | 0.469 |
| Baseline SBP (mmHg) | 152.76 ± 24.34 | 152.50 ± 24.38 | 154.96 ± 23.94 | 0.330 |
| Baseline DBP (mmHg), median (IQR) | 82.00 (74.00–92.00) | 82.00 (74.00–92.00) | 83.00 (77.00–94.50) | 0.194 |
| NIHSS on admission, median (IQR) | 3.0 (1.0–6.0) | 2.5 (1.0–5.0) | 9.5 (4.0–13.0) | <0.001 |
| Previous stroke, n (%) | 141 (14.5%) | 121 (13.9%) | 20 (19.2%) | 0.148 |
| Hypertension, n (%) | 746 (76.7%) | 665 (76.6%) | 81 (77.9%) | 0.095 |
| Diabetes, n (%) | 390 (40.1%) | 356 (41.0%) | 34 (32.7%) | 0.855 |
| CAD, n (%) | 21 (2.2%) | 21 (2.4%) | 0 (0.0%) | 0.155 |
| AF, n (%) | 118 (12.1%) | 100 (11.5%) | 18 (17.3%) | 0.088 |
| Thrombolysis, n (%) | 38 (3.9%) | 34 (3.9%) | 4 (3.8%) | 0.971 |
| Dysphagia, n (%) | 130 (13.4%) | 109 (12.6%) | 21 (20.2%) | 0.031 |
| Mechanical ventilation, n (%) | 223 (22.9%) | 198 (22.8%) | 25 (24.0%) | 0.783 |
| Use of nasogastric tubes, n (%) | 95 (9.8%) | 78 (9.0%) | 17 (16.3%) | 0.017 |
| A2DS2 score, median (IQR) | 1.0 (1.0–3.0) | 1.0 (1.0–3.0) | 3.0 (1.0–5.0) | <0.001 |
| RBC (×1012/L), median (IQR) | 4.45 (4.14–4.77) | 4.45 (4.16–4.77) | 4.38 (3.98–4.68) | 0.061 |
| Leukocyte (×109/L), median (IQR) | 6.72 (5.57–8.26) | 6.58 (5.50–7.92) | 8.36 (6.32–11.05) | <0.001 |
| Neutrophils (×109/L), median (IQR) | 4.24 (3.26–5.67) | 4.14 (3.21–5.36) | 6.15 (4.21–8.41) | <0.001 |
| Monocyte (×109/L), median (IQR) | 0.51 (0.39–0.67) | 0.50 (0.38–0.64) | 0.68 (0.45–1.00) | <0.001 |
| Lymphocyte (×109/L), median (IQR) | 1.64 (1.28–2.07) | 1.67 (1.32–2.09) | 1.30 (1.03–1.69) | <0.001 |
| PLT (×109/L), median (IQR) | 219.00 (182.00–257.50) | 219.00 (184.00–257.50) | 215.00 (171.25–258.75) | 0.291 |
| FBG (mmol/L), median (IQR) | 5.60 (4.80–7.43) | 5.60 (4.80–7.50) | 5.80 (4.90–7.20) | 0.788 |
| Scr (μmol/L), median (IQR) | 71.00 (59.00–84.00) | 71.00 (59.00–84.00) | 71.00 (58.00–85.00) | 0.744 |
| GFR, median (IQR) | 90.90 (75.30–101.70) | 91.15 (75.65–102.80) | 86.60 (73.40–95.60) | 0.015 |
| MLR, median (IQR) | 0.31 (0.23–0.43) | 0.30 (0.22–0.41) | 0.53 (0.33–0.71) | <0.001 |
| PLR, median (IQR) | 131.23 (102.58–172.27) | 128.75 (100.95–168.66) | 155.44 (127.03–208.18) | <0.001 |
| Stroke etiology, n (%) | <0.001 | |||
| Atherosclerosis | 763 (78.5%) | 693 (79.8%) | 70 (67.3%) | |
| Cardioembolism | 126 (13.0%) | 96 (11.1%) | 30 (28.8%) | |
| Small vessel occlusion | 63 (6.5%) | 60 (6.9%) | 3 (2.9%) | |
| Other causes | 20 (2.0%) | 19 (2.2%) | 1 (1.0%) |
SBP, systolic blood pressure; DBP, diastolic blood pressure; NIHSS, National Institute of Health Stroke Scale; CAD, coronary artery disease; AF, atrial fibrillation; PLT, platelet; FBG, fasting blood glucose; GFR, glomerular filtration rate; MLR, monocyte-to-lymphocyte ratio; PLR, platelet-to-lymphocyte ratio.