Table 2.
Baseline characteristics of AIS patients in different MLR tertiles.
| MLR tertiles | ||||
|---|---|---|---|---|
| Tertile 1 | Tertile 2 | Tertile 3 | P-value | |
| n = 323 | n = 323 | n = 322 | ||
| (<0.2513) | (0.2513–0.3843) | (>0.3843) | ||
| SAP, n (%) | 13 (4%) | 21 (6.5%) | 70 (21.7%) | <0.001 |
| Age (years), median (IQR) | 64.0 (58.0–70.0) | 66.0 (58.0–73.0) | 70.0 (62.0–79.0) | <0.001 |
| Male, n (%) | 165 (51.1%) | 208 (64.4%) | 243 (75.5%) | <0.001 |
| Current smoking, n (%) | 130 (40.2%) | 128 (39.6%) | 134 (41.6%) | 0.871 |
| Drinking, n (%) | 121 (37.5%) | 120 (37.2%) | 120 (37.3%) | 0.997 |
| Baseline SBP (mmHg) | 152.23 ± 22.89 | 154.55 ± 24.92 | 151.31 ± 25.08 | 0.218 |
| Baseline DBP (mmHg), median (IQR) | 82.00 (74.00–91.00) | 82.00 (74.00–92.00) | 83.00 (75.00–92.25) | 0.699 |
| NIHSS on admission, median (IQR) | 2.0 (1.0–4.0) | 3.0 (1.0–6.0) | 4.0 (2.0-9.0) | <0.001 |
| Previous Stroke, n (%) | 47 (14.6%) | 47 (14.6%) | 47 (14.6%) | 1.000 |
| Hypertension, n (%) | 258 (79.9%) | 250 (77.4%) | 234 (72.7%) | 0.250 |
| Diabetes, n (%) | 159 (49.2%) | 122 (37.8%) | 107 (33.2%) | <0.001 |
| CAD, n (%) | 2 (0.6%) | 10 (3.1%) | 8 (2.5%) | 0.070 |
| AF, n (%) | 32 (9.9%) | 50 (15.5%) | 36 (11.2%) | 0.076 |
| Thrombolysis, n (%) | 16 (5.0%) | 9 (2.8%) | 13 (4.0%) | 0.422 |
| Dysphagia, n (%) | 39 (12.1%) | 42 (13.0%) | 49 (15.2%) | 0.485 |
| Mechanical ventilation, n (%) | 64 (19.8%) | 84 (26.0%) | 74 (23.0%) | 0.166 |
| Use of nasogastric tubes, n (%) | 22 (6.8%) | 34 (10.5%) | 39 (12.1%) | 0.067 |
| A2DS2 score, median (IQR) | 1.0 (0.0–2.0) | 1.0 (1.0-3.0) | 2.0 (1.0–4.0) | <0.001 |
| RBC (×1012/L), median (IQR) | 4.46 (4.16–4.77) | 4.44 (4.17–4.74) | 4.45 (4.06–4.80) | 0.597 |
| Leukocyte (×109/L), median (IQR) | 6.27 (5.29–7.43) | 6.56 (5.47–7.91) | 7.63 (5.95–0.90) | <0.001 |
| Neutrophils (×109/L), median (IQR) | 3.64 (2.93–4.47) | 4.28 (3.22–5.27) | 5.41 (3.94–7.39) | <0.001 |
| Monocyte (×109/L), median (IQR) | 0.38 (0.32–0.48) | 0.51 (0.42–0.62) | 0.70 (0.55–.086) | <0.001 |
| Lymphocyte (×109/L), median (IQR) | 2.06 (1.68–2.46) | 1.66 (1.39–2.01) | 1.27 (1.00–1.59) | <0.001 |
| PLT (×109/L), median (IQR) | 228.00 (187.00–263.00) | 219.00 (186.00–254.00) | 211.50 (171.00–252.75) | 0.134 |
| FBG (mmol/L), median (IQR) | 5.50 (4.70–7.40) | 5.60 (4.80–7.75) | 5.80 (4.90–7.50) | 0.304 |
| Scr (μmol/L), median (IQR) | 66.00 (57.00–78.00) | 72.00 (58.00–85.00) | 73.00 (61.50–90.00) | 0.113 |
| GFR, median (IQR) | 92.70 (80.20–103.20) | 89.70 (75.80–102.00) | 88.00 (70.95–100.40) | 0.001 |
| MLR, median (IQR) | 0.20 (0.17–0.23) | 0.31 (0.28–0.35) | 0.51 (0.43–0.65) | <0.001 |
| PLR, median (IQR) | 108.16 (88.24–133.16) | 130.40 (105.65–165.63) | 163.09 (129.84–214.51) | <0.001 |
| Stroke etiology, n (%) | <0.001 | |||
| Atherosclerosis | 270 (83.6%) | 264 (81.7%) | 225 (69.9%) | |
| Cardioembolism | 17 (5.3%) | 28 (8.7%) | 81 (25.2%) | |
| Small vessel occlusion | 26 (8.0%) | 25 (7.7%) | 12 (3.7%) | |
| Other causes | 10 (3.1%) | 6 (1.8%) | 4 (1.2%) | |
SBP, systolic blood pressure; DBP, diastolic blood pressure; NIHSS, National Institute of Health Stroke Scale; CAD, coronary artery disease; AF, atrial fibrillation; PLT, platelet; FBG, fasting blood glucose; GFR, glomerular filtration rate; MLR, monocyte-to-lymphocyte ratio; PLR, platelet-to-lymphocyte ratio.