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. 2020 Oct 6;11:575809. doi: 10.3389/fneur.2020.575809

Table 4.

Results of ROC analysis about biomarkers with SAP.

AUC Cutoff Youden index Sensitivity (%) Specificity (%) PPV (%) NPV (%) P-value
MLR 0.756 0.49 0.433 56.73 86.57 33.7 94.2 <0.0001
PLR 0.637 134.47 0.255 70.19 55.32 15.9 93.9 <0.0001
Leukocyte 0.681 8.31 0.323 52.88 79.42 23.6 93.3 <0.0001
Monocyte 0.673 0.67 0.311 52.88 78.24 22.6 93.2 <0.0001
Lymphocyte 0.686 1.41 0.306 60.58 70.02 19.6 93.7 <0.0001
A2DS2 0.685 2.50 0.309 60.58 70.28 19.6 93.7 <0.0001
MLR+ A2DS2 0.794 0.12 0.468 70.19 76.62 26.5 95.5 <0.0001

MLR, monocyte-to-lymphocyte ratio; PLR, platelet-to-lymphocyte ratio.