Table 2.
Neuropeptide Y receptors in immune cells.
| Species | Tissue | Cell type | Receptorisoform | Molecular level | Reference |
|---|---|---|---|---|---|
| Rat | Peripheral blood | Granulocyte | Y1R, Y2R, Y5R | Protein | (34) |
| Peripheral blood | Monocyte | Y1R, Y2R, but not Y5R | mRNA | (35, 36) | |
| Spleen | Lymphocyte | Y1R | mRNA | (37) | |
| Dental pulp | CD43+-granulocyte CD4+-lymphocyte |
Y1R | Protein | (38) | |
| Air-pouch | Granulocyte | Y1R, Y2R, Y5R | Protein | (39) | |
| Retinal | CD11b+ microglia | Y1R, Y2R | Protein | (40) | |
| Mouse | Bone marrow | Macrophage | Y1R, Y2R | mRNA | (6, 19) |
| Bone marrow | Dendritic cell | Y1R, Y2R, Y4R, Y5R | mRNA | (24, 41) | |
| Lymph node | T/B lymphocyte | Y1R | mRNA | (42) | |
| Spleen | Leukocyte | Y1R, Y2R, Y4R, Y5R, Y6R | mRNA | (15) | |
| Adipose tissue | Macrophage | Y1R, Y2R | mRNA | (24) | |
| – | N9 Microglia cell line |
Y1R, Y2R, Y5R | mRNA Y1 (mRNA and protein) |
(28) | |
| Human | Peripheral blood | Neutrophil | Y1R, Y2R, Y4R, Y5R | mRNA | (41) |
| Infantile hemangioma | T/B lymphocyte (CD45+) and mast cells (tryptase) | Y1R | Protein | (43) | |
| Pig | Hippocampi | Microglial | Y1R | mRNA | (27) |