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Increased P2X7R-associated immunoreactivity in striatal sections from HD patients (CTRL n = 3, HD n = 3). Immunohistochemistry assay was carried out with (A) the C-terminus directed antibody or (B) the N-terminus directed antibody. In both cases, an augmented signal was observed in HD sections when compared to controls. Dash line boxes show the zoomed areas (i;ii) in both cases.
