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TGFβ-stimulated PDGFRβ regulates mTORC1signaling. Mesangial cells were treated with 0.1 µm JNJ (panels A, B, E, G, and I) or transfected with siRNAs against PDGFRβ or scramble RNA (C, D, F, H, and J) prior to incubation with 2 ng/ml TGFβ. The cleared cell lysates were immunoblotted with indicated antibodies.
