TABLE 1.

MIC distribution of seven antimicrobial agents for 366 N. gonorrhoeae isolates from Shanghai.

MICs (mg/L)
Antimicrobials	0.002	0.004	0.008	0.016	0.03	0.06	0.125	0.25	0.5	1	2	4	8	16	32	64	≥128	≥256
Ceftriaxone
na		5	11	39	135	110	46	16	1	3
Cum%b		1.4	4.4	15	51.9	82	94.5	98.9	99.2	100
Cefixime
n		2	5	22	63	125	78	37	23	7	1	3
Cum%		0.5	1.9	7.9	25.1	59.3	80.6	90.7	97	98.9	99.2	100
Azithromycin
n			1	2	14	36	101	116	63	8	4	2	9	3				7
Cum%			0.3	0.8	4.6	14.5	42.1	73.8	91	93.2	94.3	94.8	97.3	98.1				100
Ciprofloxacin
n	0	1	0	1	0	0	0	0	0	6	20	53	81	173	31
Cum%	0	0.3	0.3	0.5	0.5	0.5	0.5	0.5	0.5	2.2	7.7	22.1	44.3	91.5	100
Penicillin
n			0	0	0	0	2	5	4	53	95	63	17	75	52
Cum%			0	0	0	0	0.5	1.9	3	17.5	43.4	60.7	65.3	85.8	100
Tetracycline
n			0	0	0	0	2	12	27	102	107	17	1	29	69
Cum%			0	0	0	0	0.5	3.8	11.2	39.1	68.3	73	73.2	81.1	100
Spectinomycin
n											0	18	65	170	106	6	1
Cum%											0	4.9	22.7	69.1	98.1	99.7	100

Vertical lines indicate the breakpoint concentrations for each antimicrobial. Breakpoints: MICs > 0.125 mg/L for ceftriaxone or cefixime, ECOFF value is 1 mg/L for azithromycin, MICs > 0.06 mg/L for ciprofloxacin MICs > 1 mg/L for penicillin or tetracycline, and MICs > 64 mg/L for spectinomycin (EUCAST, 2020). ^aNumber of isolates. ^bCumulative percentage.