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. 2020 Oct 6;11:537205. doi: 10.3389/fendo.2020.537205

Figure 3.

Figure 3

Mature oocyte yield by level of LH-like activity. (A) Median (IQR) of the mature oocyte yield (number of mature oocytes divided by the number of follicles of 12 to 19 mm in diameter on day of trigger) by categories of serum hCG at 24 h (n = 161). Categories were compared by the Kruskal-Wallis test with post-hoc Dunn’s multiple comparison test. (B) Median (IQR) of the mature oocyte yield by categories of serum LH at 4 h after GnRHa (n = 151). Categories were compared by Kruskal-Wallis test with post-hoc Dunn’s multiple comparison test. (C) Median (IQR) of the mature oocyte yield by categories of serum LH at 12 h after GnRHa is presented (n = 152). Categories were compared by Kruskal-Wallis test with post-hoc Dunn’s multiple comparison test. (D) Median (IQR) of the mature oocyte yield by categories of serum LH at 12 h after kisspeptin (n = 142). Categories were compared by the Kruskal-Wallis test with post-hoc Dunn’s multiple comparison test. (E) The proportion of women achieving the median mature oocyte yield with hCG used as a trigger were compared by categories of serum hCG at 24 h: <80 (n = 16), 80–160 (n = 107), > 160 (n = 38). Categories were compared by logistic regression: P = 0.13. (F) The proportion of women achieving the median mature oocyte yield with GnRHa were compared by serum LH at 4 h: <100 iU/L (n = 28), 100–199 iU/L (n = 96), >200 iU/L (n = 27). Categories were compared by logistic regression: The odds of achieving the median mature oocyte yield was increased by 4.22-fold (95% CI 1.37–13.02; P = 0.012) if LH at 4 h following GnRHa was at least 200 iU/L compared to <100 iU/L. (G) The percentage achieving the median mature oocyte yield with GnRH used as a trigger were compared by serum LH at 12 h: <25 iU/L (n = 42), 25–49.9 iU/L (n = 79), >50 iU/L (n = 31). Categories were compared by logistic regression P = 0.29. (H) The percentage achieving the median mature oocyte yield after kisspeptin by serum LH at 12 h: <5 iU/L (n = 18), 5–9.9 iU/L (n = 34), >10 iU/L (n= 58) was compared by logistic regression. The odds of achieving the median mature oocyte yield was increased by 4.6-fold (95% CI 1.4–14.6; P = 0.010) if LH at 12 h following kisspeptin was >10 iU/L compared to <5 iU/L. **P < 0.01.