Skip to main content
. 2020 Oct 6;11:537205. doi: 10.3389/fendo.2020.537205

Figure 5.

Figure 5

Progesterone rise during oocyte maturation. (A) Change in progesterone at 12 h (nmol/L) after hCG trigger predicted the number of mature oocytes retrieved by simple linear regression (n= 159). Number of mature oocytes retrieved = 0.204 x change in progesterone at 12 h (nmol/L) + 6.60, r2 = 0.27, P < 0.0001. (B) Change in progesterone at 24 h (nmol/L) after hCG trigger predicted the number of mature oocytes retrieved by simple linear regression (n= 161). Number of mature oocytes retrieved = 0.098 x change in progesterone at 24 h (nmol/L) + 6.8, r2 = 0.23, P < 0.0001. (C) Change in progesterone at 12 h (nmol/L) after GnRHa trigger predicted the number of mature oocytes retrieved by simple linear regression (n= 151). Number of mature oocytes retrieved = 0.133 x change in progesterone at 12 h (nmol/L) + 8.37, r2 = 0.29, P < 0.0001. One outlier has not been shown on the graph. (D) Change in progesterone at 12 h (nmol/L) after kisspeptin trigger predicted the number of mature oocytes retrieved by simple linear regression (n = 143). Number of mature oocytes retrieved = 0.297 x change in progesterone at 12 h (nmol/L) + 4.83, r2 = 0.18, P < 0.0001. (E) Median (IQR) of change in progesterone at 12 h (nmol/L) divided by number of mature oocytes after hCG by categories of change in serum hCG at 12 h (iU/L) (n = 159). Categories were compared by the Kruskal-Wallis test with post-hoc Dunn’s multiple comparison test. (F) Median (IQR) of change in progesterone at 12 h (nmol/L) divided by number of mature oocytes after GnRH by categories of change in LH at 12 h (iU/L) (n = 151). Categories were compared by the Kruskal-Wallis test with post-hoc Dunn’s multiple comparison test. One outlier has not been shown on the graph. (G) Median (IQR) of change in progesterone at 12 h (nmol/L) divided by number of mature oocytes after kisspeptin by categories of change in LH at 12 h (iU/L) (n = 151). Categories were compared by the Kruskal-Wallis test with post-hoc Dunn’s multiple comparison test. (H) Median (IQR) of change in progesterone at 12 h divided by number of mature oocytes after each trigger is presented: hCG (n = 159); GnRHa (n = 151), kisspeptin (n = 137). Categories were compared by Kruskal-Wallis test with post hoc Dunn’s multiple comparison test. Four outliers were not shown on the graph. *P < 0.05, **P < 0.01,****P < 0.0001.