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. 2020 Aug 6;4:100035. doi: 10.1016/j.yjsbx.2020.100035

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This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Fig. 5 — Conformational switching of the FMN riboswitch aptamer through mutually exclusive coaxial stacking. Cartoons of apo-6WJR (A) and holo-3F2Q (B), showing the coaxial alignment of P3/P4 (cyan) or P1/P6 with FMN (magenta), respectively, depicted as molecular surfaces. (C-D) Expanded view of the coaxial junction, as observed in apo-6WJR (C) and holo-3F2Q (D), that enables conformational switching of the aptamer through mutually exclusive coaxial stacking interactions that exist in the presence or absence of ligand.