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. 2020 Oct 6;11:540878. doi: 10.3389/fneur.2020.540878

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Copyright © 2020 Serdar, Kempe, Herrmann, Picard, Remke, Herz, Bendix, Felderhoff-Müser and Sabir.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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CXCL1 protein expression in different brain regions after inflammation-sensitized hypoxic-ischemic brain injury. Twenty-four hours after hypoxia-ischemia the expression of CXCL1 protein is not regulated in cortex (A), hippocampus (HIP) (B) or thalamus (TH) (C) from animals of both genders (Sham n = 7, LPS n = 5, Veh/HI n = 9, LPS n = 8). A significant upregulation is determined in cortex of males after inflammation-sensitized hypoxic-ischemic brain injury (A), whereas there was no gender specific upregulation in hippocampus (B) or thalamus (C) (Sham n = 4 males, LPS n = 4 males, Veh/HI n = 4 males, LPS n = 4 males). *p < 0.05, **p < 0.01.